Critical Immune Defense

Rated 4.7 out of 5
Based on 929 reviews
Sale price$65.00 USD
Size: 1 Bottle
Free shipping on subscriptions & orders $75 or more.

Protect Your Pet from Life-Threatening Disease. A safe, all-natural immune booster that can add years to the life of your pet. Made in the USA.

✔︎  Boosts immune system
✔︎  Reduces inflammation
✔︎  Promotes normal cell growth
✔︎  Protects against toxins in food, water & environment
✔︎  Supports long-term health in dogs and cats

    Strengthens the Immune System

    Boosts the growth of "good" cells that fight disease and are essential for your pet’s long-term health.

    Promotes Normal Cell Growth

    Improves the immune system’s ability to monitor cell development and eliminate abnormalities.

    Can Extend Your Pet's Life

    Includes powerful antioxidants that reduce cellular aging and promote greater health & longevity.

    Protects Against Diseases

    Eliminates harmful pathogens such as bacteria and viruses that cause inflammation and infection.

    Works With Prescription Medications

    Great for pets on chemotherapy treatment, prescription steroids, pain medication & more.

    Backed By Science

    Asian cultures have used these all-natural ingredients to treat diseases and cancers for 1,000's of years.

    Your Pet's Immune System Is the Key to Its Health

    In today’s world, viruses and diseases are rampant, and it can be challenging to protect your pet. Let’s face it. Your dog and cat lives in a world filled with contamination. They spend 90% of their waking hours on the floor, mopping up toxins, chemicals, and pollutants. The household cleaning products, fertilizer on the lawn, and preservatives in their foods can be harmful.

    Bacteria, airborne contaminants, and viruses transmitted by humans can challenge their health. Most pets do not eat an optimal diet, and likely do not get as much exercise as they require.

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    50%

    Cancer Rates are skyrocketing

    More dogs and cats are being diagnosed with cancer than ever before.

    According to the Veterinary Cancer Society, almost 50% of all dogs and 32% of all cats over the age of 10 will develop cancer. Younger pets are also increasingly at risk.

    “Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”

    - Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.

    “One of the things that can be helpful is supporting your pet’s immune system with antioxidants to help its body to use its own natural defenses against disease. Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards. According to Dr. Edwards, another way to protect your pets is with all-natural health supplements.

    Pet Owners CAN Make A Difference

    “It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins.”

    Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.

    “Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”

    Mushrooms = Anticancer Activity

    “As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and mmunomodulatory properties that may help fight cancer and certain other diseases.”

    - Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.

    More dogs and cats are being diagnosed with cancer than ever before.

    According to the Veterinary Cancer Society, almost 50% of all dogs and 32% of all cats over the age of 10 will develop cancer. Younger pets are also increasingly at risk.

    “Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”

    - Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.

    “One of the things that can be helpful is supporting your pet’s immune system with antioxidants to help its body to use its own natural defenses against disease. Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards. According to Dr. Edwards, another way to protect your pets is with all-natural health supplements.

    Pet Owners CAN Make A Difference

    “It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins.”

    Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.

    “Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”

    Mushrooms = Anticancer Activity

    “As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and mmunomodulatory properties that may help fight cancer and certain other diseases.”

    - Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.

    The doctors agree

    Dr. Frank Markland

    Professor of Biochemistry and Molecular Medicine at the University of Southern California Keck School of Medicine.

    Dr. Shawn Messonnier

    Veterinary Medicine and author of "The Natural Vet's Guide to Preventing and Treating Cancer in Dogs"

    Dr. Jennifer Edwards

    Ponemah Veterinary Hospital

    Where you have seen us

    Critical Immune Defense

    Key Ingredients

    Turkey Tail Mushroom

    This colorful mushroom has been used for centuries in Asia to treat disease and contains high levels of active compounds that have been proven to inhibit the growth of cancerous tumors.

    Reishi Mushroom

    This woody fungi is known as one of the top natural superfoods and has been used for 1000s of years to fight inflammation, cancer, heart disease, hormonal imbalances and more.

    Shiitake Mushroom

    According to the Journal of Nutrition, shiitake mushrooms provide antiviral, antibacterial and antifungal protection and help to control blood sugar and reduce inflammation.

    Maitake Mushroom

    Maitake mushrooms are loaded with vitamins and active ingredients that stimulate the immune system and promote natural hormone balance and healthy cell growth.

    White Turmeric Root Extract

    Turmeric has been used for centuries to reduce pain and inflammation. Its active ingredient, curcumin, has proven to be effective at blocking the growth of certain cancers and protecting against neurodegenerative diseases, arthritis, cardiovascular risks and
    liver damage.

    Ingredients & Usage Direction:

    (Approximately 70 Scoops Per Container)

    (Approximately 70 Scoops Per Container)

    The all-natural solution. Trusted by veterinarians.

    Originally designed for veterinarians, VetSmart Formulas delivers the clinical-strength, quality and efficacy veterinarians demand of solutions they provide and recommend.

    Critical Immune Defense is 100% safe to use, has NO side effects, and can be used in conjunction with chemotherapy, steroid treatments and other medications.

    No Artificial Colors

    No Artificial Flavors

    Wheat-free

    Made In The USA To The Highest Quality Standards

    VetSmart Formulas is made in the USA in FDA audited facilities which adhere to cGMP and are audited by Underwriter Labs.

    Every ingredient is carefully inspected and tested before processing, ensuring a consistently safe, high-quality product for your beloved dog’s health.

    Frequently Asked Questions

    Happy Customer Reviews

    average rating 4.7 out of 5
    Based on 929 reviews
    • 5 Stars
      769 Reviews
    • 4 Stars
      95 Reviews
    • 3 Stars
      46 Reviews
    • 2 Stars
      7 Reviews
    • 1 Star
      12 Reviews
    93% of reviewers would recommend this product to a friend
    Effectiveness
    Rated 0 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Pet Happiness
    Rated 1 on a scale of minus 2 to 2, where minus 2 is Bummed, 0 is Just Right and 2 is Tail Wagging
    Will Eat Product
    Rated 1 on a scale of minus 2 to 2, where minus 2 is Nibbled, 0 is Enjoyed and 2 is Devoured
    Customer photos and videos
    929 Reviews
    Reviewed by Daisy W.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    7 - 10 Years
    Dog Breed
    Cane Corso
    Pet Problem(s)
    • Limp
    • Low Energy
    • Joint Pain

    It works wonder to my dogs

    it helps my cane corso’s allergies. And we noticed for adding this to her meal every day, her coat is super shiny and he hasn’t been limping. and my two little fur babies loves it and their coat are so shiny and it give the three of them lots of energy

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    Effectiveness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Pet Happiness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Bummed, 0 is Just Right and 2 is Tail Wagging
    Will Eat Product
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Nibbled, 0 is Enjoyed and 2 is Devoured
    Was this helpful?

    Pet Wellness Direct

    Hi Daisy! 🐾 Thanks for sharing how our Critical Immune Defense has worked wonders for your beautiful Cane Corso! 🌟 It's heartwarming to hear it's helped with allergies, boosted their coat's shine, and even stopped them from limping! 🎉 🐶💕

    Reviewed by Diane C.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    Pitbull Terrier
    Pet Problem(s)
    • Limp
    • Cancer

    I truly believe it saved my girl

    My female putbull was diagnosed with lymphoma back in 2020. We did chemo for 2 yrs. During this time I found the product and started using it on all my dogs, even healthy ones. We are now in almost 4 yrs later and my girl Haven has been in remission for almost 2 yrs. I only give thr product in the dinner feeding. I believe it saved her.

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    Effectiveness
    Rated 1 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Pet Happiness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Bummed, 0 is Just Right and 2 is Tail Wagging
    Will Eat Product
    Rated 0 on a scale of minus 2 to 2, where minus 2 is Nibbled, 0 is Enjoyed and 2 is Devoured
    Was this helpful?

    Pet Wellness Direct

    Hi Diane, 🐾 It's incredible to hear how Critical Immune Defense has played a role in Haven's journey to remission, especially after her battle with lymphoma. Your commitment to her health and well-being is truly remarkable. We're honored to have been a part of her healing journey, and we're sending all our best wishes for continued health and happiness for Haven and all your furry companions. 🌟

    Reviewed by Sharon T.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    3 - 5 Years
    Dog Breed
    Golden Retriever
    Pet Problem(s)
    • Tumor

    Amazing product, very effective!

    We were so impressed by Critical Immune Defense that we’ve been telling others about it. Our 4 year old Golden Retriever had lumps all over her body. We weren’t impressed by the options our vet gave us so we did research ourselves, and we’re so happy we found Critical Immune Defense. We wanted to take a holistic route for her care and this is definitely the way to go to get rid of lumps and tumors. This was very effective. Our dog shows no more signs of lumps, they all went away. Thank you so much for this product!

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    Effectiveness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Pet Happiness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Bummed, 0 is Just Right and 2 is Tail Wagging
    Will Eat Product
    Rated 1 on a scale of minus 2 to 2, where minus 2 is Nibbled, 0 is Enjoyed and 2 is Devoured
    Was this helpful?

    Pet Wellness Direct

    Thank you, Sharon, for your wonderful review! 🐾 We're thrilled to hear about your pup's amazing progress with Critical Immune Defense. Your dedication to her health is inspiring, and I'm honored our product has been a part of her journey. Here's to many more joyful, lump-free days ahead! 🌟

    Reviewed by Debbie S.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    American Staffy
    Pet Problem(s)
    • Tumor
    • Inflammation

    Seems to help

    We have been using it on our pups for about 3 months. They are 12 and 8. The oldest had a fatty tumor about the size of a half dollar that has shrunk significantly. She has cushings and hypothyroidism also so any health boosters are a plus. The younger one is on it also. Everything helps.

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    Effectiveness
    Rated 1 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Pet Happiness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Bummed, 0 is Just Right and 2 is Tail Wagging
    Will Eat Product
    Rated -1 on a scale of minus 2 to 2, where minus 2 is Nibbled, 0 is Enjoyed and 2 is Devoured
    Was this helpful?

    Pet Wellness Direct

    Hi Debbie, your review made our day! 🐾 It's so great to hear how Critical Immune Defense has helped both your pups, especially your 12-year-old, with her battle against a fatty tumor alongside cushings and hypothyroidism. Seeing the tumor shrink significantly is incredibly encouraging. Here's to continued health and vitality for your furry companions! 🌟

    Reviewed by Kary K.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    Golden Retriever
    Pet Problem(s)
    • Low Energy
    • Tumor

    Excellent product

    My 10 yr old golden retriever has been more active and is eager to play and walk. His fatty tumor has decreased by 1/2 it’s original size

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    Effectiveness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Pet Happiness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Bummed, 0 is Just Right and 2 is Tail Wagging
    Will Eat Product
    Rated 0 on a scale of minus 2 to 2, where minus 2 is Nibbled, 0 is Enjoyed and 2 is Devoured
    Was this helpful?

    Pet Wellness Direct

    Hi Kary, 🐾 It's fantastic to hear how Critical Immune Defense has positively impacted your 10-year-old Golden Retriever, especially with his increased activity levels and the significant reduction in his fatty tumor. Here's to many more joyful walks and playful moments ahead! 🌟